Biotech HPLC Systems

Sykam biotech systems are designed for applications where chemical inertness and biocompatibility are critical. All wetted components β€” pump heads, autosampler, valves, fittings, and columns β€” can be specified in PEEK, PTFE, PVDF, or PPS. This eliminates metal contact with sensitive biomolecules and enables reliable work with aggressive buffers, high-salt eluents, and biological samples at any pH.

Fully Inert Fluid Path

PEEK or PTFE pump heads, PEEK autosampler (S 5250 or S 5300), PEEK injection valves (S 6110 / S 6120), PEEK fittings and column hardware β€” complete biocompatibility for the most sensitive biomolecules.

Amino Acid Analyser S 433

The S 433 is a dedicated biotech instrument for amino acid profiling. All buffer-contacting parts are in PEEK, PTFE, or PVDF. Cooled reagent compartment under inert gas. Suitable for physiological samples (plasma, urine, CSF) and protein hydrolysates.

Ion Chromatography S 150

Fully PEEK S 150 IC module for cation and organic acid analysis in biological fluids. Combines conductivity detection with the auto-suppressor for maximum sensitivity.

S 1610 Syringe Pump

Pulse-free solvent delivery for post-column reagent addition in bioanalytical workflows. Compatible with high biomass content. Inert wetted surfaces throughout.

S 5250 / S 5300 Autosamplers

Double-needle injection design prevents septum-particle blockages. Sample temperature control +4 to +60Β°C. Injection precision < 0.25% RSD. Pre-column derivatisation and sample dilution options available.

Application

System

Amino acid profiling (physiological)

S 433 Amino Acid Analyser

Protein hydrolysate analysis

S 433 Amino Acid Analyser

Polyamine analysis

S 433 with Ninhydrin or OPA

Carbohydrate determination

S 433 with Cu-Bicinchoninate

Organic acids in urine/plasma

S 150 IC System

Biopharmaceutical purity

Analytical HPLC (PEEK)