Engineering & Custom Solutions
Chromatography, Designed for You
At Sykam, we don’t just make components — we design complete chromatography systems from concept to commissioning. Built in Germany, our integrated solutions unite separation science, precision engineering, electronics, and software to deliver purpose-built performance for your exact application.
Ready-to-run
Pre-Configured Analytical Systems
For laboratories that need proven, ready-to-run performance, Sykam offers pre-configured system platforms. The S 433 Amino Acid Analyzer integrates quaternary gradient pump, autosampler, column thermostat, post-column reactor, and dual-channel photometer into one automated platform. The S 150 Ion Chromatography system combines conductivity detection, auto-suppression, column oven, and pump in a modular stack. The S 600 Series HPLC covers analytical through semi-preparative workflows with UV/Vis, PDA, RI, or ELSD detection. Each system ships tested, documented, and ready to produce results on day one.
Tailored solutions
Custom Systems Built for Your Application
When standard configurations don't fit, Sykam's engineering team designs custom chromatography systems tailored to your specific analytical or process challenge. Multi-valve switching configurations for automated column selection or sample routing. Multi-detector setups combining conductivity, UV/Vis, and RI on a single chromatographic line. Automated pre-concentration systems for ultra-trace ion analysis in high-purity water. Specialized preparative platforms with high-flow PEEK pumps (up to 1,000 mL/min), CNC-machined inert PEEK columns, and fraction collection control. Radio-HPLC systems with shielded gamma detection for radiopharmaceutical quality control. Every custom system uses the same modular architecture and Chromstar 7 software control.
From method to plant
Lab to Production Scale-Up
Sykam supports the full scale-up pathway — from analytical method development through pilot-scale validation to turnkey production chromatography plants. We optimize separation parameters at analytical scale, design the scale-up using our preparative pump and column portfolio, and engineer the production system with integrated process monitoring, automated valve switching, and quality assurance instrumentation. Preparative PEEK columns (50–70 mm ID, pressure-tested to 150 bar) enable metal-free industrial separations impossible with conventional glass column systems.
Modules & integration
OEM Modules & System Integration
Sykam supplies branded or unbranded OEM modules to instrument manufacturers and system integrators worldwide. Pumps, detectors, autosamplers, column ovens, valves, and degassers — each available as standalone modules with full technical documentation.
Our S 4115/S 4120 column ovens, S 6000 Series valves, and S 7515 vacuum degassers are already integrated into third-party analytical platforms across multiple industries.
- Compact stackable form factors (396 × 165 × 478 mm)
- Universal power supply (100–250V)
- RS232 / Chromstar 7 control interfaces
Where Engineering Meets Software